caGrid-Enabled caBIGTM Silver Level Compatible Head and Neck Cancer Tissue Database System
Haibin Wang *, 1, Erik Bouzyk 1, Anna Kuehn 2, 3, Susan Muller 2, 3, Zhengjia Chen 1, 6, Fadlo R Khuri 4, Dong M Shin4, André Rogatko 5, Mourad Tighiouart 1, 6
Identifiers and Pagination:Year: 2010
First Page: 171
Last Page: 178
Publisher Id: TOMINFOJ-4-171
Article History:Received Date: 2/11/2009
Revision Received Date: 23/4/2010
Acceptance Date: 21/6/2010
Electronic publication date: 1/9/2010
Collection year: 2010
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
There are huge amounts of biomedical data generated by research labs in each cancer institution. The data are stored in various formats and accessed through numerous interfaces. It is very difficult to exchange and integrate the data among different cancer institutions, even among different research labs within the same institution, in order to discover useful biomedical knowledge for the healthcare community. In this paper, we present the design and implementation of a caGrid-enabled caBIGTM silver level compatible head and neck cancer tissue database system. The system is implemented using a set of open source software and tools developed by the NCI, such as the caCORE SDK and caGrid. The head and neck cancer tissue database system has four interfaces: Web-based, Java API, XML utility, and Web service. The system has been shown to provide robust and programmatically accessible biomedical information services that syntactically and semantically interoperate with other resources.